Education

• B.S.  University of Massachusetts  1989
• Ph.D.  University of New Mexico  1994
• Dept of Pathology, PD  Indiana University  1995
• Biochemistry and Molecular Biology, PD  Indiana University  1996

Background

• 2022-present: Associate Chair, Department of Environmental and Occupational Health, Indiana University - Bloomington
• 2021-present: US Environmental Protection Agency, Special Government Employee. Science Advisory Board (SAB) for PFAS Chemicals, Member
• 2016-present: Associate Professor with Tenure, Department of Environmental and Occupational Health, Indiana University, Bloomington, IN
• 2011-2015: Associate Professor, Department of Environmental and Occupational Health, Indiana University- Bloomington
• 2010-2011: Assistant Professor (visiting), Department of Environmental Health, Indiana University- Bloomington
• 2005-2010: Assistant Professor (research track), Department of Pharmacology and Toxicology, Indiana University, School of Medicine, Indianapolis, IN
• 1996-2004: Assistant Scientist, Department of Pharmacology and Toxicology,Indiana University School of Medicine
• 2003-2004: Deputy Director, Department of Toxicology, State of Indiana
• 2001-2003: Associate Director, Department of Toxicology, State of Indiana
• 1996-2001: Assistant Director, Department of Toxicology, State of Indiana

Scholarly Interest

• Contribution of Environmental Chemicals on Human Diseases
• Toxicology of PFAS Exposure
• Environmental Health
• Obesity and Cancer
• Cancer Biology

Selected Publications

Articles

Klaunig, J.E., Kamendulis, L.M. (2010) Carcinogenicity. In Lamb, J. (Ed.) Comprehensive Toxicology 2nd Edition. (in press).

Klaunig, J.E., Kamendulis, L.M., and Hocevar, B.A. (2010) Oxidative stress and damage in chemical carcinogenesis. Toxicological Pathology. 38: 96-109.

Roberts, RA, Ganey, PE, Ju, C, Kamendulis, L.M., Rusyn, I, Klaunig, JE (2007). Role of the Kupffer cell in mediating hepatic toxicity and carcinogenesis. Toxicol. Sci. 96(1):2-15

Li F, Downing BD, Smiley LC, Mund JA, Distasi MR, Bessler WK, Sarchet KN, Hinds DM, Kamendulis LM, Hingtgen CM, Case J, Clapp DW, Conway SJ, Stansfield BK, Ingram DA Jr. (2014). Neurofibromin-deficient myeloid cells are critical mediators of aneurysm formation in vivo. Circulation. 129(11):1213-24.

Hocevar BA, Kamendulis LM, Pu X, Perkins SM, Wang ZY, Johnston EL, DeWitt JM, Li L, Loehrer PJ, Klaunig JE, Chiorean EG. (2014). Contribution of environme! nt and genetics to .pancreatic cancer susceptibility. PLoS One. 9(3):e90052

Kamendulis LM, Wu Q, Sandusky GE, Hocevar BA. (2014). Perfluorooctanoic acid exposure triggers oxidative stress in the mouse pancreas. Toxicol Rep. 1:513-521.

Wang ZY, Burlak C, Klaunig JE, Kamendulis LM.(2014) Development of a cytokine-producing immortalized murine Kupffer cell line (2014). Cytokine. 70(2):165-72.

Gupta SK, Kamendulis LM, Clauss MA, Liu Z. (2016) A randomized, placebo-controlled pilot trial of N-acetylcysteine on oxidative stress and endothelial function in HIV-infected older adults receiving antiretroviral treatment. AIDS. 30(15):2389-91.

Temkin, AM.,Hocevar, BA., Andrews, DQ., Naidenko, OV., Kamendulis,LM.,(2020). Application of the Key Characteristics of Carcinogens framework to assess

Per and Plyfluoroalkyl Substances (PFAS). Int. J. Environ. Res. Public. Health 17(5):1668-. (PMID: 32143379)

Hocevar, SE., Kamendulis, LM., Hocevar, BA.(2020). Perfluorooctanic Acid (PFOA) activates the unfolded protein response in pancreatic acinar cells. J.Biochem. Mol. Toxicol. 34(11):e22561. doi:10.1002/jbt.22561. Epub 2020 Jun 24. Online ahead pf print.(PMID: 32578922)

Kamendulis, LM., Hocevar, JM., Sandusky, GE. & Hocevar, BA.(2022). Promotion of pancreatic cancer by perfluorooctanic acid (PFOA). Carcinogenesis 43(5):469-478. doi:10.1093/carcin/bgac005. (PMID: 35022659; PMCID: PMC9167031).